PhD candidate Somalisa Pan published a principal project of her PhD, investigating a putative lipase protein that she discovered in collaboration with the lab's first-ever undergraduate researcher, Julia Terrell, and characterized with the help of recently graduated undergraduate, Mary Erdmann. The protein, previously named PA14_04030 but renamed BipL (for biofilm-impacting phospholipase), was originally uncovered by Soma and Julia as restoring colony wrinkling to a smooth colony when the bipL gene was deleted. Subsequent experiments showed that BipL harbors a conserved lipase signature motif, and that mutation of the active-site Ser residue phenocopies the bipL deletion. Congratulations Soma, Mary, and Julia! The paper is available in ASM's open-access mSphere journal at https://doi.org/10.1128/msphere.00374-23.
Pan publishes lipase work
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